講師資料
Talks：
Gut Microbiota and Sleep Disorder
Name：
李立昂(Li-Ang Lee)
Position：
Professor
Affiliation：
1. Department of Otorhinolaryngology - Head and Neck Surgery, Sleep Center, Chang Gung Memorial Hospital, Linkou Main Branch, Taoyuan, Taiwan
2. Faculty of Medicine, Graduate Institute of Clinical Medicine Sciences, Chang Gung University, Taoyuan, Taiwan
3. School of Medicine, National Tsing Hua University, Hsinchu, Taiwan
Email：
Photo：
Research Interests：
Sleep Medicine, Laryngology, Infectious Disease, Brain Sciences, Medical Education
Selected Publications：
1. Lu CT, Li HY, Lee GS, Huang YS, Huang CG, Chen NH, Lee LA (Corresponding Author). Snoring sound energy as a potential biomarker for disease severity and surgical response in childhood obstructive sleep apnea: a pilot study. Clin Otolaryngol. 2019;44(1):47-52. (IF: 2.696, Ranking: 7/41)
2. Li HY, Tsai MS, Huang CG, Wang RYL, Chuang LP, Chen NH, Liu CH, Hsu CM, Cheng WN, Lee LA (Corresponding Author). Alterations in Alzheimer's Disease-Associated Gene Expression in Severe Obstructive Sleep Apnea Patients. J Clin Med. 2019;8(9):1361. (IF: 5.668, Ranking: 15/160)
3. Li HY, Tsai MS, Huang CG, Wang RYL, Chuang LP, Chen NH, Liu CH, Hsu CM, Cheng WN, Lee LA (Corresponding). Alterations in Alzheimer's Disease-Associated Gene Expression in Severe Obstructive Sleep Apnea Patients. J Clin Med. 2019;8(9):1361. (IF: 5.688; ranking: 10/160)
4. Chuang HH, Huang CG, Chuang LP, Huang YS, Chen NH, Li HY, Fang TJ, Hsu JF, Lai HC, Chen JY, Lee LA (Corresponding). Relationships Among and Predictive Values of Obesity, Inflammation Markers, and Disease Severity in Pediatric Patients with Obstructive Sleep Apnea Before and After Adenotonsillectomy. J Clin Med. 2020;9(2):579. (IF: 5.688; ranking: 15/160)
5. Tsai MS, Li HY, Huang CG, Wang RYL, Chuang LP, Chen NH, Liu CH, Yang YH, Liu CY, Hsu CM, Cheng WN, Lee LA (Corresponding Author). Risk of Alzheimer's Disease in Obstructive Sleep Apnea Patients With or Without Treatment: Real-World Evidence. Laryngoscope. 2020;130(9):2292-2298. (IF: 2.465, Ranking: 10/42)
6. Hsin LJ, Chuang HH, Lin MY, Fang TJ, Li HY, Liao CT, Kang CJ, Chen TC, Huang CG, Yen TC, Lee LA (Corresponding Author). Laryngeal Helicobacter pylori Infection and Laryngeal Cancer-Case Series and a Systematic Review. Microorganisms. 2021;9(6):1129. (IF: 4.152, Ranking: 37/136)
7. Chuang HH, Hsu JF, Chuang LP, Chiu CH, Huang YL, Li HY, Chen NH, Huang YS, Chuang CW, Huang CG, Lai HC, Lee LA (Corresponding Author). Different Associations between Tonsil Microbiome, Chronic Tonsillitis, and Intermittent Hypoxemia among Obstructive Sleep Apnea Children of Different Weight Status: A Pilot Case-Control Study. J Pers Med. 2021;11(6):486. (IF: 4.433; ranking: 10/102)
8. Chuang HH, Liu CH, Wang CY, Lo YL, Lee GS, Chao YP, Li HY, Kuo TBJ, Yang CCH, Shyu LY, Lee LA (Corresponding Author). Snoring Sound Characteristics are Associated with Common Carotid Artery Profiles in Patients with Obstructive Sleep Apnea. Nat Sci Sleep. 2021;13:1243-1255. (IF: 5.346; ranking: 40/208)
9. Tsai MS, Chen HC, Li HY, Tsai YT, Yang YH, Liu CY, Lee YC, Hsu CM, Lee LA. Sleep Apnea and Risk of Influenza-Associated Severe Acute Respiratory Infection: Real-World Evidence. Nat Sci Sleep. 2022 May 10;14:901-909. (IF: 5.346; ranking: 40/208)
10. Chuang HH, Wang CY, Chuang LP, Huang YS, Li HY, Fang TJ, Lin RH, Lee LA. The 3% Oxygen Desaturation Index is an Independent Risk Factor for Hypertension Among Children with Obstructive Sleep Apnea. Nat Sci Sleep. 2022 Jun 16;14:1149-1164. (IF: 5.346; ranking: 40/208)
Abstract：
Disruptions of normal sleep may disturb the balance of psycho-physical health; therefore, sleep disorders may interfere with the homeostasis of hormone levels, mood, and body weight. Current evidence supported a close relationship between gut microbiota and sleep disorders. The gut microbiota affects its host in many ways; in contrast, sleep disorders can alter microbiota composition and cause dysbiosis. These directional relationships between gut microbiota and sleep disorders may result in metabolic disorders, mood disorders, and other complications. In this talk, we will explore what is present in the literature on the link between gut microbiota and sleep disorders in humans.