| Talks： |
| The experiences of using Wakix |
| Name： |
| Professor Gert Jan Lammers |
| Position： |
| Full professor department of neurology |
| Affiliation： |
| Leiden University Medical Center (LUMC)
Albinusdreef 2, Leiden, The Netherlands
Stichting Epilepsy Instellingen Nederland (SEIN)
Achterweg 3, Heemstede, The Netherlands
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| Email： |
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| Photo： |
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| Research Interests： |
| Central Disorders of Hypersomnolence |
| Selected Publications： |
(1) Hypocretin (orexin) deficiency in human narcolepsy. Nishino et al. Lancet. 2000.
(2) The clinical features of cataplexy: a questionnaire study in narcolepsy patients with and without hypocretin-1 deficiency. Overeem S. van Nues et al. Sleep Med 2011
(3) Intermediate hypocretin-1 cerebrospinal fluid levels and typical cataplexy: their significance in the diagnosis of narcolepsy type 1. van der Hoeven AE. et al. Sleep. 2022.
(4) Hypocretin-1 measurements in cerebrospinal fluid using radioimmunoassay: within and between assay reliability and limit of quantification. van der Hoeven AE. et al. Sleep. 2022.
(5) Reduced Numbers of Corticotropin-Releasing Hormone Neurons in Narcolepsy Type 1. Shan L et al. Ann Neurol. 2022.
(6) Diagnosis of central disorders of hypersomnolence: A reappraisal by European experts. Lammers GJ et al. Sleep Med Rev. 2020.
(7) European guideline and expert statements on the management of narcolepsy in adults and children. Bassetti CLA. et al. J Sleep Res. 2021.
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| Abstract： |
| Drug treatment is an important pillar in the treatment of narcolepsy. Several new agents have become available over the past decades. One of the most recent is pitolisant. Pitolisant has a unique mechanism of action compared to the other commonly used agents. The place of pitolisant and the other available agents in the treatment of narcolepsy will be discussed. |
| 2023年會： |
10/29 12:30 【信東】
The experiences of using Wakix [會議室2]
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