講師資料
Talks：
Long-Term Physiological Monitoring for Sleep and Circadian Biomarkers: Towards Individualized Risk-Based Care
應用長期生理監測數據以提取睡眠與晝夜節律生物標記：邁向個人化風險導向照護
Name：
林澂（Chen Lin）
Position：
Professor
Affiliation：
Department of Biomedical Sciences and Engineering, National Central University
Email：
Photo：
Research Interests：
1. Physiological Signal Analysis and translational researches
2. Real-World Applications of portable and wearable medical devices
3. Sleep Medicine
Selected Publications：
1. Chen Lin, Wei-Chih Chin, Yu-Shu Huang, Kuo-Chung Chu, Teresa Paiva, Chia-Chi Chen, Christian Guilleminault (2021). Different circadian rest-active rhythms in Kleine-Levin syndrome: a prospective and case-control study. Sleep, 44(9): zsab096.
2. Chen Lin, I-Ming Chen, Hai-Hua Chuang, Zih-Wen Wang, Hsiao-Han Lin Yu-Hsuan Lin (2023) Examining Human-Smartphone Interaction as a Proxy for Circadian Rhythm in Patients with Insomnia: A Cross-Sectional Study. Journal of Medical Internet Research 25:e48044
3. Hai-Hua Chuang, Yu-Hsuan Lin, Li-Ang Lee, Hsiang-Chih Chang, Guan-Jie She, Chen Lin* (2024) The optimal measurement period of actigraphy for circadian rhythm in relation to adiposity: A retrospective case-control study. Sleep Medicine 122:1-7
4. Hua-Yu Lin, Chun-Tung Nien, Chia-Chi Chen, Il-Ing Hong, Chen Lin*, Chia-Mo Lin (2025) Optimizing treatment of the novel intra-oral negative pressure for obstructive sleep apnea. Sleep and Breathing, 29, 115
5. Han-Luen Huang, Chia-Hsiu Chang, Men‑Tzung Lo, Chen Lin* (2024) Diagnostic Potential of Combined Photoplethysmography and Ankle-Brachial Index in Peripheral Arterial Disease: A Duplex Ultrasonography-Based Comparative Study. Journal of the American Heart Association, 13(19): e034625
6. Zeus Harnod*, Chen Lin*, Hui-Wen Yang, Zih-Wen Wang, Han-Luen Huang, Tse-Yu Lin, Chun-Yao Huang, Lian-Yu Lin, Hsu-Wen V. Young, Men-Tzung Lo (2024) A transferable in-silico augmented ischemic model for virtual myocardial perfusion imaging and myocardial infarction detection. Medical Image Analysis 103087
7. Hsin-Yi Wang, Men-Tzung Lo, Kun-Hui Chen, Susan Mandell, Wen-Kuei Chang, Chen Lin*, Chien-Kun Ting (2021) Strong Early Phase Parasympathetic Inhibition Followed by Sympathetic Withdrawal During Propofol Induction: Temporal Response Assessed by Wavelet-Based Spectral Analysis and Photoplethysmography. Frontiers in Physiology, 705153.
Abstract：
Human behaviors and physiology can now be continuously monitored through a wide range of wearable and mobile technologies. Beyond traditional actigraphy, novel parameters capturing the regularity and variability of minute-to-minute, hourly, and day-to-day patterns have been developed. These measures have been associated with diverse health outcomes, including cancer, cardiovascular disease, and mood disorders. This talk will highlight how long-term physiological and behavioral data streams can be transformed into digital biomarkers of sleep and circadian health, and how these markers may inform individualized, risk-based care. Furthermore, multimodal signals such as photoplethysmography (PPG), electrocardiography (ECG), and smartphone usage data can be integrated to enhance early risk detection and enable more precise, personalized interventions. 
2025年會：